F-FDG PET and Tc-MDP Findings in McCune-Albright Syndrome

Received 7/9/2003; revised 7/23/2003; accepted 8/10/2003. For correspondence or reprints contact: Yeh-You Shen, M.D., Department of Nuclear Medicine, Shin Kong Wu Ho-Su Memorial Hospital. 95 Wen-Chang Road, Shih Lin District, Taipei 111, Taiwan. Tel: (886)2-28332211 ext. 2280, Fax: (886)2-28389489, E-mail: [email protected] A 57-year-old female underwent whole-body F-fluorodeoxyglucose positron emission tomography (FDGPET) study for health examination. There is increased FDG uptake in the left scapula, the left side ribs and bilateral femora. Fibrous dysplasia, sexual precocity and hyperthroidism history was then told. She also received thyroidectomy and I radioiodine therapy for hyperthyroidism. She then underwent Tc-MDP bone scintigraphy the next day to evaluate the extent of polyostotic fibrous dysplasia. The location of FDG uptake showed similar pattern as the blood pool phase bone scintigraphy. Discrepancy was noticed in the skull, the left humerus and the right side ribs between FDGPET images and delayed phase bone scintigraphy. The image findings of this patient suggest that FDG uptake within the lesions of fibrous dysplasia is highly related to the blood perfusion status of the lesions.